Kisa Gotami was the wife of a wealthy man of Savatthi. She had only one child. When her son was old enough to start running about, he caught a disease and died. Kisa Gotami was greatly saddened. Unable to accept that her son was dead and could not be brought back to life again, she took him in her arms and went about asking for medicine to cure him. Everyone she encountered thought that she had lost her mind. Finally, an old man told her that if there was anyone who could help her, it would be the Buddha.
In her distress, Kisa Gotami brought the body of her son to the Buddha and asked him for a medicine that would bring back his life. The Buddha answered: "I shall cure him if you can bring me some white mustard seeds from a house where no one has died". Carrying her dead son, she went from door to door, asking at each house. At each house the reply was always that someone had died there. At last the truth struck her, "No house is free from death". She laid the body of her child in the wood and returned to the Buddha, who comforted her and preached to her the truth.